Pair Name | Anacardic Acid, Fluorouracil | ||
Phytochemical Name | Anacardic Acid (PubChem CID: 167551 ) | ||
Anticancer drug Name | Fluorouracil (PubChem CID: 3385 ) | ||
Structure of Phytochemical |
Download
2D
MOL
3D
MOL
|
||
Structure of Anticancer Drug |
Download
2D
MOL
3D
MOL
|
Pair Name | Anacardic Acid, Fluorouracil | |||
Disease Info | [ICD-11: 2C10] | Pancreatic cancer | Investigative | |
Gene Regulation | Up-regulation | Expression | CHMP1A | hsa5119 |
Up-regulation | Phosphorylation | TP53 | hsa7157 | |
In Vitro Model | Capan-2 | Pancreatic ductal adenocarcinoma | Homo sapiens (Human) | CVCL_0026 |
BxPC-3 | Pancreatic ductal adenocarcinoma | Homo sapiens (Human) | CVCL_0186 | |
PANC-1 | Pancreatic ductal adenocarcinoma | Homo sapiens (Human) | CVCL_0480 | |
Result | Our data suggests that Anacardic Acid might be a promising complementary supplement to slow the initiation or progression of pancreatic cancer. |
No. | Title | Href |
---|---|---|
1 | Anacardic acid inhibits pancreatic cancer cell growth, and potentiates chemotherapeutic effect by Chmp1A - ATM - p53 signaling pathway. BMC Complement Altern Med. 2018 Feb 20;18(1):71. doi: 10.1186/s12906-018-2139-3. | Click |